Please visit my old site which has over innovative 950 blog notes -just restarting and also eventially mirroring now: painmuse.org
Demonstrated in mice, inhibition of spinal microglia and reduced spinal inflammatory response to spinal botulinum in sciatic nerve damage scenario. Might this offer scenario for pretreatment on surgical procedures in given peripherally?Continue reading “Botulinum Works in Part by Inhibiting Spinal Microglia”
Putting a probe up epidural canal, pulse radiofrequency for 240-360 seconds, and then withdraw catheter can give 50%+ VAS pain drop lasting 1- 3 months. It may stand as an alternative to Steroids or Midazolam epidurally.Continue reading “New Hope For Spinal Stenosis, Spondylolithesis and Disc Herniation -Pulse Radiofrequency Epidurally”
Nonspecific Low Back Pain (nsLBP) is the bane of human and has a lifetime prevalence of 70%. New treatments are welcome though results are confusing.Continue reading “Effects of Extracoporeal Shock Wave Therapy (rESWT) on Chronic Nonspecific Low Back Pain”
Melatonin can induce sleep and reduce cortisone stress but this was done in Zebra Fish… Lunkes LC, Paiva IM, Egger RC, Braga WF, Alvarez-Leite JI, da Cunha Barreto-Vianna AR, Murgas LDS. Melatonin administration attenuates acute stress by inducing sleep state in zebrafish (Danio rerio). Comp Biochem Physiol C Toxicol Pharmacol. 2021 Apr 7;246:109044. https://pubmed.ncbi.nlm.nih.gov/33838315/ “Melatonin […]
Am J Emerg Med. 2021 Mar;41:84-89.doi: 10.1016/j.ajem.2020.12.066. Epub 2020 Dec 28.Is “pain before vomiting” useful?: Diagnostic performance of the classic patient history item in acute appendicitisToshihiko Takad et al Comment – Finding pain before vomiting helps with the diagnosis but can miss 5/6 cases if absent.
I have seen a case that I read in:
I have 4 patients that she is a composite of so I’d like to go over what made a difference to them. Most of the treatments are out of the box treatments that can be helpful.
Continue reading “Chronic Severe Failed neck Surgery Pains”
Standard practice is to add colchicine to allopurinol in first 6 months of gout treatment. Allopurinol treatment dissolves crystals of uric acid which can irritate tissues in that process. ” Subjects treated with colchicine experienced fewer total flares (0.52 vs 2.91, p = 0.008), fewer flares from 0 to 3 months (0.57 vs 1.91, p = 0.022), fewer flares 3–6 months (0 vs 1.05, p = 0.033), less severe flares as reported on VAS (3.64 vs 5.08, p =0.018), and fewer recurrent gout flares (p = 0.001). Colchicine was well tolerated.”
Re older antidepressants – A metanalysis of studies concluded the benefits were “small”Salerno, Stephen M., Robert Browning, and Jeffrey L. Jackson. “The effect of antidepressant treatment on chronic back pain: a meta-analysis.” Archives of Internal Medicine 162.1 (2002): 19-24.“In conclusion, adjunct antidepressant therapy at doses therapeutic for depression is associated with a small but significant […]
Excessive sweating in buttock/groin area called Perineal Hyperhidrosis can be embarrassing and I’ve seen recent request for advice re this.