Pancreatic Cancer – fungal and Mast Cell connection

Malassezia is well known for its association with facial skin rash Seborrheic Dermatitis. It has been found teaming around pancreatic cancer tissue in mice and humans and there is even the suggestion it might be oncogenic. Mast cell are found around  pancreatic cancer cells as well, and a ketotifen, a drug to control mast cell degranuation, might help in pain control.  Pancreatic cancer tends to occur in cases who had previous pancreatic issues and diabetes, smokers and ppi users; prophylactic metformin could reduce those chances by over 50%

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