Chronic prostatism causes chronic pelvic pain and voiding issues that are chronic and pervasive with little relief beyond alpha blockers like tamsolusin. Now tadalafil (trade name Cialis) 5 mg daily can reduce symptoms by 60% in one month and more from there.
Benelli, Andrea, et al.
Once-daily 5 mg tadalafil oral treatment for patients with chronic prostatitis/chronic pelvic pain syndrome.
Therapeutic Advances in Urology (2018): 1756287218808677.
https://journals.sagepub.com/doi/full/10.1177/1756287218808677
- 14 documented cases
- analysis every 4 weeks showed dramatic reductions in symptoms chronic prostatism symptom index (CPISI) p < 0.000002 and International Prostatitis Symptom Index (IPPS) p< 0.0001
- Idea is that relaxation of prostatic duct smooth muscles increases washout of toxic prostatic products with reduced prostatic inflammation.
- well tolerated though one was excluded from study because he got muscle pains from drug.
- Results detailed per month:
Comment – results are amazing for a disorder that left men with chronic poorly understood chronic pain and urinary symptoms.