IV Cortisone For Sciatica Not Great

It has been bandied about for years that IV steroids might effect relief in sciatica. Now it looks like little benefit –  though if they did the stats right, they could show a little on day three.


Pain Med. 2018 Dec 21. doi: 10.1093/pm/pny252. [Epub ahead of print]
Short-term Efficiency and Tolerance of Ketoprofen and Methylprednisolone in Acute
Sciatica: A Randomized Trial.
Gastaldi R al
https://www.ncbi.nlm.nih.gov/pubmed/30576555

  • Intravenous injections of methylprednisolone (60 mg/d), ketoprofen (200 mg/d) or placebo for five days
  • 17-19 in each group

Results:
sciatica_ivsteroids

Comment – they did stats work that suggested day 3 maybe better with IV steroids but I’m not seeing it…

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