Vaccinations Help In Elderly in More Ways than One

The Pneumococcal vaccine can reduce chance of heart attack and stroke in cases over 60, and the shingles vaccine reduces stroke over 60 for 10 years.  Another study found reduced heart attack rates in those having a flu shot.  After all the bad press, this is a new view of benefits for vaccinations.

Pneumococcal

Vila-Corcoles, Angel, et al.
Clinical effectiveness of pneumococcal vaccination against acute myocardial infarction and stroke in people over 60 years: the CAPAMIS study, one-year follow-up.
BMC Public Health 12.1 (2012): 222.
https://bmcpublichealth.biomedcentral.com/track/pdf/10.1186/1471-2458-12-222

“pneumococcal vaccination was associated with a 35% (95% CI: 1% to 58%) reduction in the adjusted risk of ischaemic stroke. This result seems to be robust considering that this significant protective effect remains when people with history of prior stroke are excluded from the analysis.”

 

Influenzal

 

CMAJ. 2010 Oct 19;182(15):1617-23. doi: 10.1503/cmaj.091891.
Influenza vaccination, pneumococcal vaccination and risk of acute myocardial
infarction: matched case-control study.
Siriwardena AN, Gwini SM, Coupland CA.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952008/pdf/1821617.pdf

“Influenza vaccination had been received in the previous year by 8472 cases (52.9%) and 32 081 controls (51.2%) and was associated with a 19% reduction in the rate of acute myocardial infarction (adjusted odds ratio [OR] 0.81, 95% confidence interval [CI] 0.77-0.85). Early seasonal influenza vaccination was associated with a lower rate of acute myocardial infarction (adjusted OR 0.79, 95% CI 0.75-0.83) than vaccination after mid-November (adjusted OR 0.88, 95% CI 0.79-0.97).”

Shingles

An Association Between Herpes Zoster Vaccination and Stroke Reduction Among Elderly Individuals
John S Klaric Thomas A Beltran Bruce M McClenathan
Military Medicine, Volume 184, Issue Supplement_1, March-April 2019, Pages 126–132

“The HZ-vaccinated group aged 65–69 years reported stroke approximately 50% less than those unvaccinated (adjusted Odds Ratio [aOR] = 1.51; 99% confidence interval [CI]:1.21,1.88). Secondary analyses indicated that this benefit was among HZ-vaccinated whites (aOR = 1.6, 95%CI:1.4,2.0), but not African Americans or Hispanics.”

 

shinglevirus_protest

 

Comment – not all studies found pneumococcal vaccine helped but arguments were made that including 45-60 group diluted any effects – and other arguments about quality of study.  The benefits of the shingles vaccine were with the old vaccine. – not enough known about new one. Older Zostavax appears to wane at year 7 so a argument could be made to redo vaccine then. I had the older Zostavax and one of the new Shingrix. I guess I will have the second half of Shingrix in 7 years…

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