There are now medications for high risk or unvaccinated patients; I will not go into them. I will discuss other medications I have put in place for myself (71) and vaccinated. Sorry, Ivermectin (horse dewormer) is not on my list. They include vitamin D 50,000 u/day, fluoxamine 50 -100 mg twice daily, colchicine 0.5 mg twice daily, and L-arginine 1000 mg three times daily.
Vitamin D:
High does vitamin d did make a difference albeit it could be in deficient cases most so:
Rastogi, Ashu, et al. “Short term, high-dose vitamin D supplementation for COVID-19 disease: a randomised, placebo-controlled, study (SHADE study).” Postgraduate medical journal 98.1156 (2022): 87-90.
https://pmj.bmj.com/content/98/1156/87.abstract
They used 60,000 units vitamin D3 for 7 days.
“in intervention and control group, respectively]. 10 (62.5%) participants in the intervention group and 5 (20.8%) participants in the control arm (p<0.018) became SARS-CoV-2 RNA negative.”
I would take 50,000 units/day for at least 7 days then maybe 5000 u/day
Fluvoxamine
– “Clinicians who prescribe fluvoxamine for COVID-19 should familiarize themselves with relative contraindications and notable drug-drug interactions, including the need to limit caffeine (eTable 2 in the Supplement). The most common reported side effects from fluvoxamine in clinical trials are gastrointestinal (nausea, vomiting, diarrhea, and anorexia) and central nervous system complaints (headache, dizziness, somnolence, and nervousness).”
“both of these trials are using 50 mg twice daily of fluvoxamine, which, if unsuccessful, could indicate that 100 mg twice daily is the minimum effective dose.”
‘Depending on the scenario, the probability of any association with reduced hospitalization ranged from 94.1% to 98.6%, and the probability of moderate association ranged from 81.6% to 91.8%.’
That actually means a slight reduction
https://jamanetwork.com/journals/jamanetworkopen/article-abstract/2790742
Arginine
– health food store amino acid so safe
– dose was 1.66 g L-arginine twice a day or about three of the 1000 mg/day
– “At 10-day evaluation, 71.1% of patients in the L-arginine arm and 44.4% in the placebo arm (p < 0.01) had the respiratory support reduced” which was quite significant
https://www.sciencedirect.com/science/article/pii/S2589537021004053
Colchicine
Review of it are rather mediocre but:
– safe
-decreased covid severity so good there
– no difference in hospitalization
review here:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0266245
Vitamin C
Vitamin C in the Treatment of COVID-19.
Nutrients 13.4 (2021): 1172.
https://www.mdpi.com/2072-6643/13/4/1172/pdf
Comment – have these agents in the frig; if you can think of others that could be used, please advise